South Medford Vacations from $648

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Your South Medford Vacation

South Medford is calling! Whatever type of adventure you have in mind, you can see and experience more of this neighborhood with a South Medford vacation package. Some popular nearby attractions to visit during your trip to South Medford include Tufts University, Old Ship Street Historic District and Medford Square. Whatever your ideal South Medford vacation may look like, you can turn it into reality with Expedia.

The Latest South Medford Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A hotel room with a large bed, two bedside lamps, a headboard, a wall-mounted abstract art piece, and potted plants.
    Dec 10 - Dec 14

    Furnished Apartment Near Longwood + Flight

    North Brookline
    4 nights
    3.0 star property
    8.2/10 - Very good (17 reviews)
    Roundtrip • Los Angeles (LAX) - Boston (BOS)
    LAX - BOS • Nonstop BOS - LAX • 1 stop
    $859
    $648
    per traveler
    found 23 hours ago
    Furnished Apartment Near Longwood
  • A spacious hotel lobby with a dining area, seating, large windows, and a chandelier.
    Jan 21 - Jan 24

    Boston Harbor Hotel + Flight

    North End
    3 nights
    5.0 star property
    9.8/10 - Exceptional (1,006 reviews)
    Roundtrip • Burbank (BUR) - Boston (BOS)
    BUR - BOS • 1 stop BOS - BUR • 1 stop
    $1,557
    $973
    per traveler
    found 11 hours ago
    Boston Harbor Hotel
  • A courtyard with brick walls, outdoor seating, and potted plants.
    Jan 31 - Feb 3

    Four Seasons Hotel Boston + Flight

    Bay Village
    3 nights
    5.0 star property
    9.4/10 - Exceptional (496 reviews)
    Roundtrip • Los Angeles (QLA) - Boston (BOS)
    LAX - BOS • Nonstop BOS - LAX • 1 stop
    $1,627
    $1,120
    per traveler
    found 1 hour ago
    Four Seasons Hotel Boston
  • A spacious, elegantly designed dining area with high ceilings, chandeliers, and classic decor.
    Jan 21 - Jan 24

    The Langham, Boston + Flight

    Downtown Boston
    3 nights
    5.0 star property
    9.6/10 - Exceptional (1,005 reviews)
    Roundtrip • Burbank (BUR) - Boston (BOS)
    BUR - BOS • 1 stop BOS - BUR • 1 stop
    $1,118
    $823
    per traveler
    found 11 hours ago
    The Langham, Boston
  • Pool
    Jan 21 - Jan 24

    Raffles Boston + Flight

    Back Bay
    3 nights
    5.0 star property
    9.6/10 - Exceptional (354 reviews)
    "Amazing hotel Great rooms and helpful, professional staff. Couldn’t fault it."
    Reviewed November 8, 2026
    Roundtrip • Dallas (DFW) - Boston (BOS)
    DFW - BOS • Nonstop BOS - DFW • 1 stop
    $1,696
    $1,289
    per traveler
    found 1 day ago
    Raffles Boston

Where to stay in South Medford

Find the best South Medford areas and neighborhoods for the activities you enjoy most.
Quincy Market with an American flag, historic buildings, and a clock tower in the background.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

A historic church with a large central tower and multiple spires, surrounded by modern buildings and a public square with people and greenery.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

A city skyline at dusk with illuminated buildings reflecting on the water, a prominent bridge, and a large chain barrier along the waterfront.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

A large brick building with a golden dome, a flagpole with the American flag, and a statue in front.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

A statue of a man on horseback in a park with trees, a clock tower, and brick buildings in the background.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

South Medford Hotel Deals

A bar area with wicker chairs, a bar counter, and shelves stocked with liquor bottles.

Porter Square Hotel

Porter Square Hotel
3.0 star property
1.3 mi from South Medford
9.2 out of 10, Wonderful, (1,002 reviews)
"I was only there for a quick weekend wedding trip but the two nights were incredibly comfortable. Everything was clean. I was grateful to have some complimentary coffees available in the morning (and some waters after having a few too many after the wedding). The neighbors were quiet and the staff really did me a solid after I asked for a late checkout. Would absolutely come back."
$124 nightly
The price is $144
Nov 22 - Nov 23
Total with taxes and fees
Porter Square Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in South Medford
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.